What is the N,N-DIPROPYLTRYPTAMINE?

N,N-DIPROPYLTRYPTAMINE is , while it's Molecular Formula is C16H24N2. N,N-Dipropyl-1H-indole-3-ethanamine is a tryptamine designer drug used in toxicology studies which was one of the findings in an analysis of street drugs in seized material without primary reference standards.

What is the CAS number for N,N-DIPROPYLTRYPTAMINE?

The CAS number of N,N-DIPROPYLTRYPTAMINE is 61-52-9.

What is N,N-DIPROPYLTRYPTAMINE (61-52-9) used for?

N,N-DIPROPYLTRYPTAMINE, also known as N,N-Dipropyl-1H-indole-3-ethanamine, is a tryptamine designer drug that has been identified in toxicology studies. It is found in street drugs and is analyzed in seized material without primary reference standards.InChI:InChI=1/C16H24N2/c1-3-10-18(11-4-2)12-9-14-13-17-16-8-6-5-7-15(14)16/h5-8,13,17H,3-4,9-12H2,1-2H3

N,N-DIPROPYLTRYPTAMINE

Basic information

Product Name:N,N-DIPROPYLTRYPTAMINE
CasNo.:61-52-9
MF:C₁₆H₂₄N₂
MW:244.38

Physical and Chemical Properties

Purity:99%
Boiling Point:174-178 °C
Packing:
Throughput:

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Product Details

CasNo： 61-52-9

MF： C₁₆H₂₄N₂

Chinese Manufacturer Supply Best Quality 61-52-9 N,N-DIPROPYLTRYPTAMINE with Efficient Delivery

Molecular Formula:C16H24N2
Molecular Weight:244.38
Vapor Pressure:3.3E-06mmHg at 25°C
Melting Point:174-178 °C
Refractive Index:1.574
Boiling Point:387.4 °C at 760 mmHg
PKA:17.30±0.30(Predicted)
Flash Point:188.1 °C
PSA：19.03000
Density:1.014 g/cm³
LogP:3.83240

N,N-DIPROPYLTRYPTAMINE(Cas 61-52-9) Usage

N,N-dipropyltryptamine (DPT) is a synthetic tryptamine hallucinogen which has been used psychotherapeutically in humans. The Psychedelic N,N-Dipropyltryptamine Prevents Seizures in a Mouse Model of Fragile X Syndrome via a Mechanism that Appears Independent of Serotonin and Sigma1 Receptors.

InChI:InChI=1/C16H24N2/c1-3-10-18(11-4-2)12-9-14-13-17-16-8-6-5-7-15(14)16/h5-8,13,17H,3-4,9-12H2,1-2H3

61-52-9 Relevant articles

Binding properties of dipropyltryptamine at the human 5-HT1a receptor

Thiagaraj, Harish V.,Russo, Ethan B.,Burnett, Andrea,Goldstein, Eric,Thompson, Charles M.,Parker, Keith K.

, p. 193 - 199 (2005)

Dipropyltryptamine (DPT) is a synthetic ...

Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): Possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents

William E. Fantegrossi a , Chad J. Reissig b , Elyse B. Katz a , Haley L. Yarosh a , Kenner C. Rice c , Jerrold C. Winter b

Pharmacology Biochemistry and Behavior Volume 88, Issue 3 , January 2008, Pages 358-365

In the present studies, DPT was tested in a drug-elicited head-twitch assay in mice, and in rats trained to discriminate lysergic acid diethylamide (LSD), N,N-dimethyl-4-phosphoryloxytryptamine (psilocybin), or 3,4-methylenedioxymethamphetamine (MDMA). A separate group of rats was also trained to recognize DPT itself as a discriminative stimulus, and in all cases, the behavioral effects of DPT were challenged with the selective serotonin (5-HT)2A antagonist M100907, the 5-HT1A selective antagonist WAY-100635, or their combination.

The Psychedelic N,N-Dipropyltryptamine Prevents Seizures in a Mouse Model of Fragile X Syndrome via a Mechanism that Appears Independent of Serotonin and Sigma1 Receptors

Richa TyagiTanishka S. SarafClinton E. Canal*

ACS Pharmacol. Transl. Sci. 2023, 6, 10, 1480–1491

We show that a similar psychedelic tryptamine, N,N-dipropyltryptamine (DPT), completely prevents audiogenic seizures (AGS) in an Fmr1 knockout mouse model of fragile X syndrome at a 10 mg/kg dose but not at lower doses (3 or 5.6 mg/kg). Despite showing in vitro that DPT is a serotonin 5-HT2A, 5-HT1B, and 5-HT1A receptor agonist (with that rank order of functional potency, determined with TRUPATH Gα/βγ biosensors), pretreatment with selective inhibitors of 5-HT2A/2C, 5-HT1B, or 5-HT1A receptors did not block DPT’s antiepileptic effects; a pan-serotonin receptor antagonist was also ineffective.

61-52-9 Process route

: 61-54-1
tryptamine

: 123-38-6
propionaldehyde

: 61-52-9
Dipropyltryptamine

Conditions

Conditions	Yield
With sodium cyanoborohydride; acetic acid; In methanol; at 0 - 20 ℃; Inert atmosphere;	94%

: 61-54-1
tryptamine

: 107-08-4
1-iodo-propane

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: 61-52-9
Dipropyltryptamine

Conditions

Conditions	Yield
In diethyl ether; at 20 ℃; for 16h;	46%

61-52-9 Upstream products

3389-21-7
3-(2-bromoethyl)-1H-indole
142-84-7
di-n-propylamine
61-54-1
tryptamine
107-08-4
1-iodo-propane

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